Pure Steam & Clean Steam Validation: Quality, Sampling & Testing Guidelines Pure Steam & Clean Steam Validation: Quality, Sampling & Testing Guidelines Steam is a critical utility in pharmaceutical manufacturing, especially for sterilization, SIP (Sterilization-in-Place), and cleaning. When steam directly contacts product surfaces or sterile equipment, it must meet stringent purity and quality standards. This is where pure steam and clean steam validation becomes essential to ensure compliance with global GMP and pharmacopoeial standards. This article provides an end-to-end tutorial on how to validate pure steam and clean steam systems in pharma, including qualification stages (DQ, IQ, OQ, PQ), steam…