GMP Requirements for Validation Logs & Real-Time Recordkeeping in Pharma GMP-Compliant Validation Logs and Real-Time Recordkeeping in Pharma: Structure, Expectations, and Best Practices Logbooks are an essential component of Good Manufacturing Practice (GMP) documentation. In the context of pharmaceutical validation — including cleaning validation, equipment qualification, and process performance qualification (PPQ) — validation logs and cleaning records provide traceable, contemporaneous evidence that each step was performed according to protocol. This guide explains how to design and maintain GMP-compliant validation logs, cleaning logs, and real-time documentation practices in line with regulatory expectations from the FDA, EMA, ICH Q7/Q9, and WHO. 1….