Manual Tool & Accessory Validation in Pharma: A Step-by-Step Compliance Guide How to Validate Manual Tools and Accessories in Pharma Cleaning Processes Introduction Manual tools and accessories such as spatulas, scoops, tongs, and dismantled parts of equipment play a significant role in pharmaceutical manufacturing. Despite their simplicity, they are critical product-contact items that must be validated for cleaning effectiveness under GMP regulations. This article provides a comprehensive, step-by-step guide for validating manual cleaning of tools and accessories in compliance with FDA, EMA, and WHO guidelines. Why Manual Tools Require Cleaning Validation Although tools are often overlooked in automated cleaning validations…